Sunday, November 22, 2009

Breast Cancer Study 'Identifies Tumour-Causing Enzyme'


Scientists have identified an enzyme that is crucial for turning into breast tissue tumors, according to a study published in the journal Cell.
The Institute of Cancer Research says blocking the enzyme lysyl oxidase (LOX), reduced the size and frequency of tumors in mice.
They Say LOX stiffens collagen, a major component of the supportive tissue in the breast.
A cancer charity said the study added to Knowledge about how tumors develop.
The supportive tissue surrounding cancer cells is shaped differently Thurs healthy tissue as well as being stiffer and more fibrous.
These properties have helped doctors Thurs detect breast cancers, but until now scientists have not known what was causing these changes.
'Clear physical change'
The team at the Institute for Cancer Research, using mice, found that LOX caused the collagen to change in a process known as cross-linking, which makes the more fibrous tissue.

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